Publications

Refereed Journal Publications Since 2005

1. J.K. Stechmiller, L. Cowan, G. Schultz. The Role of Doxycycline as a Matrix Metalloproteinase Inhibitor for the Treatment of Chronic Wounds, Biol Res Nursing, in press.
2. J. Liu, M. Saghizadeh, S.S. Tuli, A.A. Kramverov, A.S. Lewin, D.C. Bloom, W.W. Hauswirth, M.G. Castro, G.S. Schultz, A.V. Ljubimov. Different Tropisms of Adenovirus and Adeno-Associated viruses to Corneal Cells: Implications for Corneal Gene Therapy. Molecular Vision, 14:2087-2096, 2008.
3. B. Baskovich, E.M. Sampson, G.S. Schultz, L.K.S. Parnell. Wound Dressing Components Degrade Proteins Detrimental to Wound Healing. International Wound J, 5:543-551, 2008.
4. B.B. Childress, G.S. Schultz, J.K. Stechmiller. Arginine Metabolites in Wound Fluids from Pressure Ulcers: A Pilot Study. Biol Res Nursing, 10:87-92, 2008.
5. M. Sisco, Z.B. Kryger, K.D. O’Shaughnessy, P.S. Kim, G.S. Schultz, X.Z. Ding, N.K. Roy, N.M. Dean, T.A. Mustoe. Antisense inhibition of connective tissue growth factor (CTGF/CCN2) mRNA limits hypertrophic scarring without affecting wound healing in vivo. Wound Rep Reg, 16:661-673, 2008.
6. C. Clement, M. Popp, D. Bloom, G. Schultz, L. Liu, D. Neumann, P. Bhattacharjee, J. Hill. Microarray analysis of host gene expression for comparison between naïve and HSV-1 latent rabbit trigeminal ganglia. Molecular Vision, 14:1209-1221, 2008.
7. J. Liu, A.S. Lewin, S.S Tuli, S.C. Ghivizzani, G.S. Schultz, D.C. Bloom. Reduction in Severity of a Herpes Simplex Virus Type 1 (HSV-1) Murine Infection by Treatment with a Ribozyme Targeting the UL20 Gene RNA. J Virology, 82:7467-7474, 2008.
8. G.A. Secker, A.J. Shortt, E. Sampson, Q.P. Schwartz, G.S. Schultz, J.T. Daniels. TGF-beta stimulated re-epithelialisation is regulated by CTGF and Ras/MEK/ERK signaling. Exp Cell Res, 314:131-142, 2008.
9. Z. Jiang, P. Yu, M. Tao, C. Fernandez, C. Ifantides, O. Moloye, G.S. Schultz, C.K. Ozaki, S.A. Berceli. TGF-β and CTGF Mediated Fibroblast Recruitment Influences Early Outward Vein Graft Remodeling. Am J Physiol Heart Circ Physiol, 293:H482-H488, 2007.
10. O. Kloeters, S-X. Jia, N. Roy, G.S. Schultz, G. Leinfellener, T.A. Mustoe. Alteration of Smad3 Signaling in ischemic Rabbit Dermal Ulcer Wounds. Wound Rep Reg, 15:341-349, 2007.
11. M.P. Popp, L. Liu, A. Timmers, D.W. Esson, L. Shiroma, C. Meyers, S. Berceli, M. Tao, G. Wistow, G.S. Schultz, M.B. Sherwood. Development of a microarray chip for gene expression in rabbit ocular research. Molecular Vision, 13:164-173, 2007.
12. O. Cheng, R. Thuillier, E. Sampson, G. Schultz, P. Ruiz, X. Zhang, P.S.T. Yuen, R.B. Mannon. Connective Tissue Growth Factor (CTGF) is a Biomarker and Mediator of Kidney Allograft Fibrosis, Am J Transplantation, 6:2292-2306, 2006.
13. S.A. Berceli, A. Jiang, N.V. Klingman, G.S. Schultz, C.K. Ozaki. Early Differential MMP-2 and -9 Dynamics During Flow Induced Arterial and Vein Graft Adaptations. J Surg Res, 134:327-334, 2006.
14. M. John-Aryankalayil, N. Dusku, C. Jaworski, C.A. Cox, G. Schultz, J. Smith, K.E. Ramsey, D.A. Stephan, T.W. Reid, D. A.
15. Carper. Microarray and Protein Analysis of Human Pterygia. Molecular Vision, 12:55-64, 2006.
16. P.J. Antonelli, G.S. Schultz, D.J. Sundin, P.A. Pemberton, P.J. Barr. Alpha 1-Antitrypsin Single Dose Adjuvant Therapy for Acute Otitis Media, Otolaryngol Head Neck Surg, 135:111-115, 2006.
17. S.S. Tuli, R. Liu, T.D. Blalock, C. Chen, M.H. Goldstein, G.S. Schultz. Immunohistochemical Localization of TGF-α, TGF-β, EGF, and their Receptors in Rat Corneas During Healing of Excimer Laser Ablation, Current Eye Res, 31:709-719, 2006.
18. D. Kilpadi, J.K. Stechmiller, B. Childress, L. Cowan, M. Comerio, K. Kieswetter, G. Schultz. Composition of Wound Fluid from Pressure Ulcers Treated with Vacuum Assisted Closure® Therapy in Home Health or Extended Care Patients: A Pilot Study. Wounds 18:119-126, 2006.
19. J.K. Stechmiller, B. Childress, L. Cowan, G. Stevens, D. Kilpadi, G.S. Schultz. Effect of Negative Pressure Wound Therapy on the Expression of TNF-α, IL-1β , MMP-2, MMP-3 and TIMP-1 in Wound Fluid of Adults with Pressure Ulcers, Wound Rep Reg, 14:371-374, 2006.
20. G.B. van Setten, L. Berglin, T.D. Blalock, G. Grotendorst, G. Schultz. Detection of CTGF in Subretinal Fluid of Retinal Detachment: Possible Contribution to Subretinal Scar Formation. Ophthalmic Res 37:289-292, 2005.
21. T.T. Thula, G.S. Schultz, C. Batich, R. Tran-Son-Tay. Effects of Epidermal Growth Factor and Basic Fibroblast Growth Factor on Irradiated Rat Parotid Glands. Ann Biomed Eng 33:685-695, 2005.
22. K.L. Watts, E.M. Sampson, G.S. Schultz, M.A. Spiteri. Simvastatin Inhibits Growth Factor Expression and Modulates Pro-Fibrogenic Markers in Lung Fibroblasts. Am J Respir Cell Mol Biol 32:290-300, 2005.
23. P.J. Antonelli, G.S. Schultz, J.S. Cantwell, D.J. Sundin, P.A. Pemberton, P.J. Barr. Inflammatory Proteases in Chronic Otitis Externa. Laryngoscope 115:651-654, 2005.

Book Chapters Since 2005

1. G.S. Schultz and P.L. Phillips. Molecular Regulation of Wound Healing. In: Acute and Chronic Wounds: Nursing Management, 4rd edition, R.A. Bryant & D.P. Nix, eds., Mosby Inc., St. Louis, MO, Chapter 5, in press.
2. J. Berlanga-Acosta, G.S. Schultz, P Lopez-Saura. Biology of the Diabetic Wound. In: Foot Ulcers: Causes, Diagnosis and Treatments, P.E. Overhaussen, ed. Nova Science Publishers, Inc., Hauppauge, NY, USA, in press.
3. S.S. Tuli, D.W. Esson, M. B. Sherwood, G.S. Schultz. Modulation of Wound Healing: Principles, Chapter 113, In: Glaucoma, T. Shaarawy, M.B. Sherwood, R. Hitchings, J.G. Crowston, eds. Elsevier, London, UK, 2009.
4. G.S. Schultz, E.A. Ayello, H. Brem. Wound Debridement. In: Essential Tissue Healing of the Face and Neck, D.A. Hom, P.A. Hebda, A.K. Gosain, C.D. Friedman, eds., B.C. Decker, Inc., Hamilton, Ontario, Canada, Chapter 26, pp. 349-366, 2009.
5. G.S. Schultz. Molecular Regulation of Wound Healing. In: Acute and Chronic Wounds: Nursing Management, 3rd edition, R.A. Bryant & D.P. Dix, eds., Mosby Inc., St. Louis, MO, Chapter 5, pp 82-99, 2007.
6. V. Jones, S. Bale, K. Harding, J Stechmiller, G. Schultz. Acute and Chronic Wound Healing. In: Wound Care Essentials: Practice Principles, S. Baranoski, and E.A. Ayello, eds., Lippincott Williams & Wilkins, Springhouse, PA, Chapter 5, pp. 64-76, 2007.
7. G.A. Chin, G.S. Schultz, R.F. Diegelmann, N. Chegini. Biochemistry of Wound Healing. In: Wound Care Practice, Paul Sheffield, ed., 2nd edition, Best Publishing Co., Flagstaff, AZ, USA, Chapter 2, pp. 51-78, 2007.
8. G. Schultz, J. Stechmiller. Bench Science Advances for Chronic Wound Care. In: Chronic Wound Care: A Clinical Source Book for Healthcare Professionals, D. L. Krasner, G. T. Rodeheaver, and R. G. Sibbald, eds., 4th edition, HMP Communications, Malvern, PA, Chapter 8, pp. 67-73, 2007.
9. G. Schultz. The Physiology of Wound Bed Preparation. In: Surgical Wound Healing, M. Granick and G. Gamelli, eds., Informa Healthcare, New York, NY, Chapter 1, pp.1-16, 2007.
10. G.S. Schultz, G.A. Chin, L.L. Moldawer, R.F. Diegelmann. Principles of Wound Healing. In: Mechanisms of Vascular Disease: A Textbook for Vascular Surgeons, M. Thompson, R Fitridge, eds., Greenwich Medical Media Ltd, London UK, Chapter 23, pp. 329-345, 2007.
11. G.A. Chin, R.F. Diegelmann, G.S. Schultz. Cellular and Molecular Regulation of Wound Healing. In: Wound Healing: Science and Practice, A. Falabella, and R.S. Kirsner, eds., Marcel Dekker, Inc. New York, NY, USA, Chapter 3, pp 17-38, 2005.
12. A. Wysocki, T. Mustoe, G. Schultz. Molecular Cell Biology of Skin. In: Encyclopedia of Molecular Cell Biology and Molecular Medicine, Wiley-VCH Verlag, Weinheim, Germany, Vol 13, pp. 217-250, 2005.
13. S.S. Tuli, M.H. Goldstein, G.S. Schultz. Modulation of Corneal Wound Healing. In: Cornea, 2nd edition, J.H. Krachmer, M. J. Mannis and E. J. Holland, eds., Mosby-Year Book, Philadelphia, PA. Chapter 9, pp.133-150, 2005.

Invited Review Articles Since 2005

1. G. Schultz, J.B. Acosta, L. Cowan, J. Stechmiller. Linking the AGE/RAGE Pathway in Diabetics with Inflammation and Topical Anti-Inflammatory Treatments of Chronic Wounds, Wound Repair Regen, in press.
2. P.L. Phillips, Q. Yang, E. Sampson, G. Schultz. Effects of Antimicrobial Agents on an In Vitro Biofilm Model of Skin Wounds, Wound Repair Regen, in press.
3. P. Phillips, E. Sampson, Q. Yang, P. Antonelli, A. Progulske-Fox, G. Schultz. Bacterial Biofilms in Wounds. Wound Healing Southern Africa, in press.
4. J.B. Acosta, D.G. del Barco, D.C. Vera, W. Savigne, P. Lopez-Saura, G.G. Nieto, G.S. Schultz. The Pro-inflammatory Environment in Recalcitrant Diabetic Foot Wounds. International Wound J, 5:530-539, 2008.
5. A. Stojadinovic, J.W. Carlson, G.S. Schultz, T.A. Davis, and E.A. Elster. Topical Advances in Wound Care. Gynecol Oncol, 111: supplement 2, S70-S80, 2008.
6. K. Harding, et al., Diagnostics in Wound Management: A Consensus Document, International Wound Journal, 5: supplement July 2008.
7. K. Harding et. al., Wound Infection in Practice, Shaping the Future: A Consensus Document, International Wound Journal, 5: supplement 3, pp 1-11, 2008.
8. S.S. Tuli, G.S. Schultz, and D.M. Downer. Science and Strategy for Preventing and Managing Corneal Ulceration. The Ocular Surface, 5:23-39, 2007.
9. M. Granick, J. Boykin, R. Gamelli, G. Schultz, M. Tenenhaus. Toward a Common Language: Surgical Wound Bed Preparation and Debridement. Wound Rep Reg, 14:S1-S10, 2006.
10. G. Schultz. Règlement Biologique du Marquage (Biological Regulation of Scarring), Journal des Plaies et Cicatrisations 54:83-88, 2006.
11. G. Schultz, D. Mozingo, M. Romanelli, K. Claxton. Wound Healing and TIME; New Concepts and Scientific Applications. Wound Rep Reg, 13 (sup 4):S1-S11, 2005.
12. G.S. Schultz, G. Ladwig, A. Wysocki. Extracellular Matrix: Review of Its Roles in Acute and Chronic Wounds. www.worldwidewounds, August, 2005.
13. R. Lobmann, G. S. Schultz, H. Lehnert. Proteases and the Diabetic Foot Syndrome – Mechanisms and Therapeutic Implications, Diabetes Care, 28:461-471, 2005.